Spontaneous malignant craniopharyngioma in an aged Wistar rat
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چکیده
منابع مشابه
Spontaneous malignant craniopharyngioma in an aged Wistar rat
Craniopharyngiomas are extremely rare epithelial tumors of the sellar region in human beings and domestic and laboratory animals. A craniopharyngioma, 0.6 cm in diameter, was observed grossly in the sellar and parasellar regions of an untreated 23-month-old male Wistar-derived rat sacrificed moribund. The tumor was composed of cords, columns, and nests of neoplastic stratified squamous epitheli...
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Previous studies indicated there is an overall increase of proteolysis in aging rat brains. We monitored the potential degradation of cytoskeletal proteins in neuronal tissue taken from cerebral cortex and cerebellum of young (3 month) and aging (17, 21 and 23.5 month) Wistar rats. We found significant age-dependent proteolysis of cytoskeletal proteins (alphaII-spectrin and microtubule-associat...
متن کامل[Craniopharyngioma--a "geographical malignant" tumour].
The craniopharyngioma is a rare dysontogenetic tumour that originates from either scattered cells of the craniopharyngeal duct or from metaplastically mutated anterior pituitary parenchyma cells. Despite being classified as a WHO-Class-I tumour, the histologically benign craniopharyngioma may display an aggressive behaviour. Like other congenital tumours, it usually becomes manifest within the ...
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An intracranial malignant teratoma was identified in a 91-day-old male Wistar rat manifesting central nervous system-related clinical signs. This tumor occupied the right midbrain and portions of the right caudal cerebrum and cranioventral cerebellum. Microscopically, the tumor contained intermingled cartilage, bone (with medullary hematopoietic tissue), fibrous connective tissue, skeletal musc...
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Spontaneous chloroleukemia occurred in three adult members of a colony of Wistar rats. The chloroleukemia from one of these rats has been maintained in random-bred Wistar rats by inoculating tumor cells from leukemic donors into suckling rats. This report describes the course and manifestations, hematology, and pathologic changes of this transplantable chloroleukemia through ten serial subtrans...
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ژورنال
عنوان ژورنال: Journal of Toxicologic Pathology
سال: 2016
ISSN: 0914-9198,1881-915X
DOI: 10.1293/tox.2016-0004